CALL FOR PAPERS MicroRNA and Tissue Injury MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats

نویسندگان

  • U. P. R. Soci
  • T. Fernandes
  • N. Y. Hashimoto
  • G. F. Mota
  • M. A. Amadeu
  • K. T. Rosa
  • M. C. Irigoyen
  • M. I. Phillips
  • E. M. Oliveira
چکیده

U. P. R. Soci, T. Fernandes, N. Y. Hashimoto, G. F. Mota, M. A. Amadeu, K. T. Rosa, M. C. Irigoyen, M. I. Phillips, and E. M. Oliveira Laboratory of Biochemistry of the Motor Activity, School of Physical Education and Sport, Hypertension Unit, Heart Institute (InCor), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil; and Laboratory of Stem Cells, Keck Graduate Institute of Applied Life Sciences, Claremont, California

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MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats.

MiRNAs regulate cardiac development, hypertrophy, and angiogenesis, but their role in cardiac hypertrophy (CH) induced by aerobic training has not previously been studied. Aerobic training promotes physiological CH preserving cardiac function. This study assessed involvement of miRNAs-29 in CH of trained rats. Female Wistar rats (n=7/group) were randomized into three groups: sedentary (S), trai...

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تاریخ انتشار 2011